NTRK3 Break Apart FISH Probe Kit
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The NTRK3 Break Apart FISH Probe Kit is designed to detect rearrangements in the
human NTRK3 gene located on chromosome band 15q25.3. In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other NTRK3 aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the NTRK3 gene – also known as TRKC, GP145-TrkC or gp145(trkC) - has been observed in medulloblastoma, fibrosarcoma, nephroma, some breast carcinoma subtypes and other malignancies.
Intended Use: To detect rearrangements in the human NTRK3 locus situated on chromosome band 15q25.3.
LSP NTRK3 5 FISH Probe: CytoGreen
LSP NTRK3 3 FISH Probe: CytoOrange
10 Tests (100 μL)
LSP NTRK3 5’ FISH Probe covers the 5’ (start) portion of the ABL2 locus and some adjacent genomic sequences. LSP NTRK3 3‘ FISH Probe covers sequences at the 3’ (end) of the gene. The two probes are flanking sequences across the NTRK3 locus in which variable breakpoints have been observed.
For Research Use Only.